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Scientists used a special imaging technique to observe how Tau protein clumps in the brain tissue of genetically modified flies in response to treatment with RI-AG03. Without the treatment (A), they saw toxic clumps of Tau fibrils (arrow) and oligomers (a
The brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell and degenerate due to the Tau protein. The red shows where Tau is building up in c
